Minor/Significance Unknown. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor.aspirin decreases effects of candesartan by pharmacodynamic antagonism. Risk of fetal compromise if given during pregnancy. Serious - Use Alternative (1)candesartan, lisinopril. diclofenac decreases effects of candesartan by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. An overdose of candesartan can cause low blood pressure and dizziness. Modify Therapy/Monitor Closely. Either increases toxicity of the other by pharmacodynamic synergism. Effect of interaction is not clear, use caution. Use Caution/Monitor. Risk of hypokalemia, especially with strong glucocorticoid activity. Use Caution/Monitor.acemetacin increases and hydrochlorothiazide decreases serum potassium. Modify Therapy/Monitor Closely. In case of overdose, call the poison control helpline at 1-800-222-1222. lofexidine, candesartan. Minor (1)hydrochlorothiazide increases levels of piperacillin by decreasing renal clearance. Use Caution/Monitor. Monitor Closely (4)candesartan, salsalate. Use Caution/Monitor. ibuprofen increases and hydrochlorothiazide decreases serum potassium. Modify Therapy/Monitor Closely. Observe for possible additive hypotensive effects during concomitant use. Coadministration of ARBs with sparsentan is associated with increased risks of hypotension, syncope, hyperkalemia, and changes in renal function (eg, acute renal failure). Risk of hypokalemia, especially with strong glucocorticoid activity. Use Caution/Monitor. .Minor (1)hydrochlorothiazide will increase the level or effect of ketorolac intranasal by acidic (anionic) drug competition for renal tubular clearance. Either increases toxicity of the other by pharmacodynamic synergism. Take it as your doctor tells you. Coadministration with drugs associated with nephrotoxicity may increase the risk for acute and/or chronic nephrotoxicity. Minor/Significance Unknown. Use Caution/Monitor.sulfasalazine decreases effects of candesartan by pharmacodynamic antagonism. hydrochlorothiazide will increase the level or effect of celecoxib by acidic (anionic) drug competition for renal tubular clearance. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Thiazide dosage >50 mg/day may increase blood glucose. Keep this medication in the container it came in, tightly closed, and out of reach of children. amoxicillin, hydrochlorothiazide. Use Caution/Monitor.candesartan and nebivolol both increase serum potassium. Minor/Significance Unknown. Use Caution/Monitor. Minor/Significance Unknown. Risk of hypokalemia, especially with strong glucocorticoid activity. hydrochlorothiazide will increase the level or effect of ofloxacin by basic (cationic) drug competition for renal tubular clearance. Use Caution/Monitor. Comment: Coadministration with medications that cause fluid and electrolyte abnormalities may increase the risk of adverse events of seizure, arrhythmias, and renal impairment.sodium sulfate/?magnesium sulfate/potassium chloride increases toxicity of hydrochlorothiazide by Other (see comment). Modify Therapy/Monitor Closely. candesartan and tolfenamic acid both increase serum potassium. penbutolol, candesartan. Monitor Closely (1)hydrochlorothiazide and olodaterol inhaled both decrease serum potassium. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. cation binding in GI tract. olmesartan increases and hydrochlorothiazide decreases serum potassium. Minor (1)rose hips will increase the level or effect of hydrochlorothiazide by acidic (anionic) drug competition for renal tubular clearance. candesartan, eplerenone. shepherd's purse, hydrochlorothiazide. triamterene increases and hydrochlorothiazide decreases serum potassium. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Monitor Closely (1)penicillin G aqueous, hydrochlorothiazide. sulfasalazine increases and hydrochlorothiazide decreases serum potassium. Thiazide dosage >50 mg/day may increase blood glucose. Minor (1)hydrochlorothiazide decreases effects of vildagliptin by pharmacodynamic antagonism. Portions of this document last updated: May 01, 2023. Thiazide dosage >50 mg/day may increase blood glucose. Thiazide diuretics can decrease insulin sensitivity thereby leading to glucose intolerance and hyperglycemia. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. Use Caution/Monitor. Use Caution/Monitor.diclofenac decreases effects of candesartan by pharmacodynamic antagonism. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (1)amoxicillin, hydrochlorothiazide. Use Caution/Monitor.pindolol, candesartan. Effect of interaction is not clear, use caution. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Modify Therapy/Monitor Closely. Monitor Closely (1)empagliflozin, hydrochlorothiazide. voclosporin, candesartan. Avoid or Use Alternate Drug. Both drugs decrease blood glucose. Minor/Significance Unknown. Minor/Significance Unknown. Drugs that act directly on the renin angiotensin system (RAS) can cause injury and death to the developing fetus. Use Caution/Monitor. pharmacodynamic synergism. WebHypertension Candesartan is indicated for the treatment of hypertension in adults and in children 1 to < 17 years of age, to lower blood pressure. Use Caution/Monitor.candesartan and tolmetin both increase serum potassium. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor.potassium chloride increases and hydrochlorothiazide decreases serum potassium. candesartan, naproxen. Risk of fetal compromise if given during pregnancy. Monitor Closely (1)maraviroc, candesartan. Minor/Significance Unknown. dopexamine, hydrochlorothiazide. Take candesartan exactly as directed. Thiazide dosage >50 mg/day may increase blood glucose. Use Caution/Monitor. WebHeart Failure in Adults What it does: Sandoz Candesartan is an angiotensin receptor blocker (ARB). Risk of hyperkalemia. Comment: Potential for increased risk of hypotension with concurrent use. hydrochlorothiazide and carbenoxolone both decrease serum potassium. Minor/Significance Unknown. Copyright 1996-2023 Cerner Multum, Inc. Either increases toxicity of the other by Other (see comment). Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Hypokalemia. hydrochlorothiazide increases levels of sulfamethoxazole by unspecified interaction mechanism. Minor (1)hydrochlorothiazide will increase the level or effect of memantine by basic (cationic) drug competition for renal tubular clearance. Mechanism: pharmacodynamic synergism. Your kidney function may also need to be checked. fludrocortisone, hydrochlorothiazide. Either increases toxicity of the other by Other (see comment). Effect of interaction is not clear, use caution. Risk of hypokalemia (theoretical). Minor/Significance Unknown. Effect of interaction is not clear, use caution. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. Either increases effects of the other by pharmacodynamic synergism. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Use Caution/Monitor. hydrochlorothiazide decreases effects of repaglinide by pharmacodynamic antagonism. The usual starting dose for hypertension is 16 mg daily, and the starting dose candesartan and nebivolol both increase serum potassium. We comply with the HONcode standard for trustworthy health information. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.mefenamic acid decreases effects of candesartan by pharmacodynamic antagonism. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor.celiprolol, candesartan. Risk of hypokalemia, especially with strong glucocorticoid activity. candesartan increases effects of insulin regular human by unspecified interaction mechanism. Use Caution/Monitor.salsalate decreases effects of candesartan by pharmacodynamic antagonism. hydrochlorothiazide decreases effects of insulin glulisine by pharmacodynamic antagonism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. Minor/Significance Unknown. Not all possible drug interactions are listed here. fenoprofen decreases effects of candesartan by pharmacodynamic antagonism. Use Caution/Monitor.Minor (1)levalbuterol, hydrochlorothiazide. candesartan, ketorolac intranasal. Either increases toxicity of the other by pharmacodynamic synergism. Do not take more or less of it or take it more often than prescribed by your doctor. Serious - Use Alternative (1)candesartan, ramipril. candesartan and potassium citrate/citric acid both increase serum potassium. Use Caution/Monitor. Minor/Significance Unknown. Effect of interaction is not clear, use caution. commonly, these are "preferred" (on formulary) brand drugs. Follow your doctor's orders or the directions on the label. Minor/Significance Unknown. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.piroxicam decreases effects of candesartan by pharmacodynamic antagonism. Do not stop taking candesartan without talking to your doctor. Either increases toxicity of the other by Other (see comment). Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)dofetilide will increase the level or effect of hydrochlorothiazide by basic (cationic) drug competition for renal tubular clearance. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Use Caution/Monitor.candesartan, oxaprozin. betaxolol, candesartan. Use Caution/Monitor. Use Caution/Monitor. Thiazide dosage >50 mg/day may increase blood glucose. It helps to control it. Stop using Atacand and tell your doctor right away if you become pregnant. In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of ARBS with drugs that affect RAAS may increase the risk of renal impairment (including acute renal failure) and cause loss of antihypertensive effect. Minor/Significance Unknown. Effect of interaction is not clear, use caution. Take the candesartan packet, or the leaflet inside it, plus any remaining medicine with you. Monitor Closely (1)irbesartan increases and hydrochlorothiazide decreases serum potassium. Concomitant use of insulin and ARBs may require insulin dosage adjustment and increased glucose monitoring. Minor/Significance Unknown. epinephrine racemic, hydrochlorothiazide. amiloride increases and hydrochlorothiazide decreases serum potassium. Monitor for signs of diminished diuresis and/or effects on blood pressure and increase dosage of the diuretic as needed. Use Caution/Monitor. Serious - Use Alternative (1)candesartan, fosinopril. Most Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Minor/Significance Unknown.hydrochlorothiazide decreases effects of metformin by pharmacodynamic antagonism. Mechanism: pharmacodynamic synergism. Monitor Closely (1)epinephrine racemic and hydrochlorothiazide both decrease serum potassium. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Consider decreasing dosage of antihypertensive agent. hydrochlorothiazide will increase the level or effect of indapamide by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Minor (1)cefadroxil will increase the level or effect of hydrochlorothiazide by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.ibuprofen IV increases and hydrochlorothiazide decreases serum potassium. You are being redirected to Modify Therapy/Monitor Closely. Use Caution/Monitor. candesartan, diclofenac. Monitor Closely (1)fentanyl intranasal decreases effects of hydrochlorothiazide by Other (see comment). Use Caution/Monitor. Effect of interaction is not clear, use caution. hydrochlorothiazide increases toxicity of lithium by decreasing elimination. When you first start treatment your doctor may gradually increase the strength of the tablets to suit your condition. Monitor Closely (1)quinidine will increase the level or effect of hydrochlorothiazide by basic (cationic) drug competition for renal tubular clearance. Minor/Significance Unknown. Serious - Use Alternative (1)hydrochlorothiazide, tretinoin topical. Greater than 50 kg: You can easily become dehydrated while taking Atacand. ibuprofen IV decreases effects of candesartan by pharmacodynamic antagonism. Do not double doses. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. ketorolac intranasal increases and hydrochlorothiazide decreases serum potassium. Atacand Descriptions Candesartan is used alone or together with other medicines to treat high blood pressure (hypertension) in adults and children 1 to 16 Contraindicated. Comment: Diuretics may cause hyperglycemia and glycosuria in patients with diabetes mellitus, possibly by diuretic-induced hpokalemia. Monitor Closely (1)candesartan increases effects of insulin detemir by unspecified interaction mechanism. Coadministration of ARBs with sparsentan is associated with increased risks of hypotension, syncope, hyperkalemia, and changes in renal function (eg, acute renal failure). WebHeart failure with impaired left ventricular systolic function in conjunction with an ACE inhibitor (under expert supervision) By mouth. empagliflozin, hydrochlorothiazide. Your doctor may occasionally change your dose. Mechanism: pharmacodynamic synergism. Additive hypotensive effects. Use Caution/Monitor.Minor (1)metaproterenol, hydrochlorothiazide. Minor (1)budesonide, hydrochlorothiazide. Use Caution/Monitor. Contraindicated. Use Caution/Monitor. Comment: Potential for increased risk of hypotension with concurrent use. Use Caution/Monitor. Effect of interaction is not clear, use caution. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Tell your doctor about all your other medicines, especially: any other heart or blood pressure medications; NSAIDs (nonsteroidal anti-inflammatory drugs) - ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. hydrochlorothiazide decreases effects of insulin lispro by pharmacodynamic antagonism. Effect of interaction is not clear, use caution. Use Caution/Monitor. hydrochlorothiazide increases toxicity of cyclophosphamide by decreasing renal clearance. Risk of hypokalemia, especially with strong glucocorticoid activity. Remember that this medicine will not cure your high blood pressure but it does help control it. AdultsAt first, 16 milligrams (mg) candesartan and 12.5 mg hydrochlorothiazide once a day. Risk of alkalosis, hypercalcemia. What should I know about storage and disposal of this medication? Minor (3)sulfamethoxazole will increase the level or effect of hydrochlorothiazide by basic (cationic) drug competition for renal tubular clearance. birch increases effects of hydrochlorothiazide by pharmacodynamic synergism. Effect of interaction is not clear, use caution. URL of this page: https://medlineplus.gov/druginfo/meds/a601033.html. WebCommon side effects. Use Caution/Monitor.Minor (1)dopexamine, hydrochlorothiazide. Monitor Closely (1)umeclidinium bromide/vilanterol inhaled and hydrochlorothiazide both decrease serum potassium. Your doctor will probably tell you not to take candesartan if you have diabetes and you are also taking aliskiren. Use Caution/Monitor. Comment: Low molecular weight heparins may suppress adrenal aldosterone secretion, which can potentially cause hyperkalemia. Use Caution/Monitor. labetalol, candesartan. Either increases toxicity of the other by pharmacodynamic synergism. methylprednisolone, hydrochlorothiazide. For adults, the usual dose is: high blood pressure 8mg to 32mg once a day. hydrochlorothiazide decreases effects of chlorpropamide by pharmacodynamic antagonism. Effect of interaction is not clear, use caution. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.aspirin/citric acid/sodium bicarbonate increases and hydrochlorothiazide decreases serum potassium. Use Caution/Monitor.ibuprofen IV decreases effects of candesartan by pharmacodynamic antagonism. Use Caution/Monitor.aspirin/citric acid/sodium bicarbonate decreases effects of candesartan by pharmacodynamic antagonism. candesartan and potassium acid phosphate both increase serum potassium. Use Caution/Monitor.candesartan, ketoprofen. Other (see comment). For adults with moderate liver problems: 8 mg per day. Minor/Significance Unknown.noni juice increases and hydrochlorothiazide decreases serum potassium. Minor/Significance Unknown. Monitor Closely (1)brimonidine increases effects of candesartan by pharmacodynamic synergism. Use Caution/Monitor.choline magnesium trisalicylate decreases effects of candesartan by pharmacodynamic antagonism. Use Caution/Monitor.labetalol increases and hydrochlorothiazide decreases serum potassium. Minor/Significance Unknown. tolfenamic acid increases and hydrochlorothiazide decreases serum potassium. Use Caution/Monitor. If candesartan does not get your blood pressure down, your doctor may want to increase the dose. Use Caution/Monitor. Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. Either increases toxicity of the other by pharmacodynamic synergism. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). All rights reserved. vilanterol/fluticasone furoate inhaled and hydrochlorothiazide both decrease serum potassium. Effect of interaction is not clear, use caution. Mechanism: pharmacodynamic synergism. fentanyl decreases effects of hydrochlorothiazide by Other (see comment). Effect of interaction is not clear, use caution. Atacand: 16 mg [scored; contains corn starch] Atacand: 32 mg [DSC] [scored] Atacand: 32 mg [scored; contains corn starch] Generic: 4 mg, 8 mg, 16 mg, 32 mg hydrochlorothiazide and olodaterol inhaled both decrease serum potassium. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Monitor Closely (1)metaproterenol and hydrochlorothiazide both decrease serum potassium. Use Caution/Monitor. Minor/Significance Unknown. Comment: Angiotensin II receptor antagonists may enhance hypoglycemic effects of antidiabetic agents by improving insulin sensitivity. commonly, these are "non-preferred" brand drugs or specialty Effect of interaction is not clear, use caution. Minor/Significance Unknown. 6 TO LESS THAN 17 YEARS: Take Atacand exactly as prescribed by your doctor. hydrochlorothiazide decreases effects of metformin by pharmacodynamic antagonism. Use Caution/Monitor. Effect of interaction is not clear, use caution. diflunisal increases and hydrochlorothiazide decreases serum potassium. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia.Minor (2)hydrochlorothiazide will increase the level or effect of trimethoprim by basic (cationic) drug competition for renal tubular clearance. Modify Therapy/Monitor Closely. Monitor Closely (1)succinylcholine increases and hydrochlorothiazide decreases serum potassium. Use Caution/Monitor.
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candesartan dosage for adults
